The field of biopharmaceuticals is playing an increasingly pivotal role in medical treatment but is encountering several challenges. One pressing issue is the short half-life of many biopharmaceutical products, which leads to rapid degradation and clearance from the patient's body, necessitating frequent dosing. In this article, we explore how half-life extension strategies in drug development...
In the complex world of molecular biology, ribosomes are more than just protein-making machines—they are dynamic hubs where regulation, adaptation, and cellular decisions take place. As researchers delve deeper into the translational landscape, a combination of traditional and cutting-edge methods is redefining how we study ribosome function. Among these, polysome profiling, ribosomal...
The promise of cancer immunotherapy rests on a detailed understanding of how tumors and immune cells interact. Tumor tissues are highly heterogeneous, containing diverse populations of malignant, stromal, and immune cells. These cellular communities shape disease progression and influence how patients respond to treatment. Traditional bulk sequencing methods blur this complexity, masking the...
In the evolving landscape of cancer research, next-generation sequencing technologies have become indispensable tools to decode the complex genetic and transcriptomic landscapes of tumors. Among the foundational steps enabling this progress are DNA and RNA library preparation techniques, which directly impact the quality and reliability of sequencing results.
DNA library...
When people think about therapeutic antibodies, the focus often turns to binding specificity, half-life, or effector functions. Yet beneath these well-known characteristics lies a subtler but equally decisive factor: glycosylation. These intricate sugar chains attached to antibodies are not passive bystanders—they actively shape how an antibody behaves, interacts, and ultimately performs...
English
French
Spanish
Portuguese
Deutsch
Turkish
Dutch
Italiano
Russian
Romaian
Portuguese (Brazil)
Tiếng Việt